2,3,5,4'-Tetrahydroxy-stilbene-2-O-beta-d-glucoside induces autophagy-mediated apoptosis in hepatocytes by upregulating miR-122 and inhibiting the PI3K/Akt/mTOR pathway: implications for its hepatotoxicity

• Những tác giả chính: Lei Yang (Tác giả), Wei Xing (Tác giả), Wang-Zhong Xiao (Tác giả), Lin Tang (Tác giả), Lu Wang (Tác giả), Meng-Jiao Liu (Tác giả), Bing Dai (Tác giả)
• Định dạng: Sách
• Được phát hành: Taylor & Francis Group, 2020-01-01T00:00:00Z.
• Những chủ đề: article
• Truy cập trực tuyến: Connect to this object online.

Context The potential hepatotoxicity of Polygoni Multiflori Radix (PMR) has attracted much attention, but the specific mechanism of inducing hepatotoxicity is still unclear due to the complexity of its components. Objective This study investigated the specific mechanism by which 2,3,5,4'-tetrah...