Tubeimoside I Antagonizes Yoda1-Evoked Piezo1 Channel Activation

• Ngā kaituhi matua: Silin Liu (Author), Xianmei Pan (Author), Wenbin Cheng (Author), Bo Deng (Author), Yu He (Author), Lei Zhang (Author), Yile Ning (Author), Jing Li (Author)
• Hōputu: Pukapuka
• I whakaputaina: Frontiers Media S.A., 2020-05-01T00:00:00Z.
• Ngā marau: article
• Urunga tuihono: Connect to this object online.

Piezo1, a mechanosensitive Ca2+-permeable non-selective cationic ion channel protein, is involved in a wide range of biological processes and plays crucial roles in vascular development. However, the pharmacology of this protein is in its infancy. Yoda1, the first specific chemical activator of Piez...