Co-Encapsulation of Simvastatin and Doxorubicin into pH-Sensitive Liposomes Enhances Antitumoral Activity in Breast Cancer Cell Lines

Doxorubicin (DOX) is a potent chemotherapeutic drug used as the first line in breast cancer treatment; however, cardiotoxicity is the main drawback of the therapy. Preclinical studies evidenced that the association of simvastatin (SIM) with DOX leads to a better prognosis with reduced side effects a...

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Main Authors: Jaqueline Aparecida Duarte (Author), Eliza Rocha Gomes (Author), André Luis Branco De Barros (Author), Elaine Amaral Leite (Author)
Format: Book
Published: MDPI AG, 2023-01-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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