Network pharmacology, molecular docking, and experimental verification reveal the mechanism of San-Huang decoction in treating acute kidney injury

• Main Authors: Jiahui Liu (Author), Zhongtang Li (Author), Yunlan Lao (Author), Xiaoming Jin (Author), Yuzhi Wang (Author), Beibei Jiang (Author), Riming He (Author), Shudong Yang (Author)
• Format: Book
• Published: Frontiers Media S.A., 2023-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Cisplatin is an effective anti-tumor drug. However, its usage is constrained by side effects such as nephron toxicity. Cisplatin-induced acute kidney injury (AKI) appears in approximately 20%-30% of cases. Hence, finding an effective protective strategy is necessary. San-Huang decoction...