Lung-Targeted Delivery of Cepharanthine by an Erythrocyte-Anchoring Strategy for the Treatment of Acute Lung Injury

• मुख्य लेखकों: Jinpeng Zheng (लेखक), Caihong Lu (लेखक), Meiyan Yang (लेखक), Jiejie Sun (लेखक), Jinbang Zhang (लेखक), Yuanyuan Meng (लेखक), Yuli Wang (लेखक), Zhiping Li (लेखक), Yang Yang (लेखक), Wei Gong (लेखक), Chunsheng Gao (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: MDPI AG, 2022-08-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

As one of the most frequent complications of critical illness, acute lung injury (ALI) carries a high risk of clinical morbidity and mortality. Cepharanthine (CPA) has significant anti-inflammatory activity, however, due to poor water solubility, low bioavailability, and short half-life, it fails to...