The Synthetic Peptide GA-Hecate and Its Analogs Inhibit Multiple Steps of the Chikungunya Virus Infection Cycle In Vitro

• Главные авторы: Gabriela Miranda Ayusso (Автор), Paulo Ricardo da Silva Sanches (Автор), Tamara Carvalho (Автор), Igor Andrade Santos (Автор), Daniel Oliveira Silva Martins (Автор), Maria Letícia Duarte Lima (Автор), Pâmela Jóyce Previdelli da Conceição (Автор), Cíntia Bittar (Автор), Andres Merits (Автор), Eduardo Maffud Cilli (Автор), Ana Carolina Gomes Jardim (Автор), Paula Rahal (Автор), Marilia Freitas Calmon (Автор)
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• Опубликовано: MDPI AG, 2023-09-01T00:00:00Z.
• Предметы: article
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Chikungunya virus (CHIKV) belongs to the <i>Alphavirus</i> genus and is responsible for significant outbreaks worldwide. Currently, there is no approved antiviral therapy against CHIKV. Bioactive peptides have great potential for new drug development. Here, we evaluated the antiviral act...