The Synthetic Peptide GA-Hecate and Its Analogs Inhibit Multiple Steps of the Chikungunya Virus Infection Cycle In Vitro

• Main Authors: Gabriela Miranda Ayusso (Author), Paulo Ricardo da Silva Sanches (Author), Tamara Carvalho (Author), Igor Andrade Santos (Author), Daniel Oliveira Silva Martins (Author), Maria Letícia Duarte Lima (Author), Pâmela Jóyce Previdelli da Conceição (Author), Cíntia Bittar (Author), Andres Merits (Author), Eduardo Maffud Cilli (Author), Ana Carolina Gomes Jardim (Author), Paula Rahal (Author), Marilia Freitas Calmon (Author)
• Format: Book
• Published: MDPI AG, 2023-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Chikungunya virus (CHIKV) belongs to the <i>Alphavirus</i> genus and is responsible for significant outbreaks worldwide. Currently, there is no approved antiviral therapy against CHIKV. Bioactive peptides have great potential for new drug development. Here, we evaluated the antiviral act...