Are thyrotropin‐releasing hormone (TRH) and analog taltirelin viable reversal agents of opioid‐induced respiratory depression?

• Main Authors: Marieke Hyke Algera (Author), Joseph F. Cotten (Author), Monique vanVelzen (Author), Marieke Niesters (Author), Martijn Boon (Author), Daniel S. Shoham (Author), Kaye E. Dandrea (Author), Rutger van derSchrier (Author), Albert Dahan (Author)
• Format: Book
• Published: Wiley, 2022-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Opioid‐induced respiratory depression (OIRD) is a potentially life‐threatening complication of opioid consumption. Apart from naloxone, an opioid antagonist that has various disadvantages, a possible reversal strategy is treatment of OIRD with the hypothalamic hormone and neuromodulator thy...