Development of a Ready-to-Use-Type RNA Vaccine Carrier Based on an Intracellular Environment-Responsive Lipid-like Material with Immune-Activating Vitamin E Scaffolds

• Main Authors: Jessica Anindita (Author), Hiroki Tanaka (Author), Ryotaro Oyama (Author), Shinya Hagiwara (Author), Daiki Shirane (Author), Sakura Taneichi (Author), Yuta Nakai (Author), Kota Tange (Author), Hiroto Hatakeyama (Author), Yu Sakurai (Author), Hidetaka Akita (Author)
• Format: Book
• Published: MDPI AG, 2023-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Because of its efficient and robust gene transfer capability, messenger RNA (mRNA) has become a promising tool in various research fields. The lipid nanoparticle (LNP) is considered to be a fundamental technology for an mRNA delivery system and has been used extensively for the development of RNA va...