A time-released osmotic pump fabricated by compression-coated method: Formulation screen, mechanism research and pharmacokinetic study

• मुख्य लेखकों: Tiegang Xin (लेखक), Yang Zhao (लेखक), Hengpan Jing (लेखक), Wenji Zhang (लेखक), Yunyun Gao (लेखक), Xinggang Yang (लेखक), Xukai Qu (लेखक), Weisan Pan (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Elsevier, 2014-08-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

In this investigation, time-released monolithic osmotic pump (TMOP) tablets containing diltiazem hydrochloride (DIL) were prepared on the basis of osmotic pumping mechanism. The developed dosage forms were coated by Kollidon®SR-Polyethylene Glycol (PEG) mixtures via compression-coated technology ins...