The Potential Effect of Insulin on AChE and Its Interactions with Rivastigmine In Vitro

• Egile Nagusiak: Tahereh Jamshidnejad-Tosaramandani (Egilea), Soheila Kashanian (Egilea), Mahsa Babaei (Egilea), Mohamed H. Al-Sabri (Egilea), Helgi B. Schiöth (Egilea)
• Formatua: Liburua
• Argitaratua: MDPI AG, 2021-11-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

There is no definite cure for Alzheimer's disease (AD) due to its multifactorial origin. Drugs that inhibit acetylcholinesterase (AChE), such as rivastigmine, are promising symptomatic treatments for AD. Emerging evidence suggests that insulin therapy can hinder several aspects of AD pathology....