1-Piperidine Propionic Acid as an Allosteric Inhibitor of Protease Activated Receptor-2

• Main Authors: Monica Chinellato (Author), Matteo Gasparotto (Author), Santina Quarta (Author), Mariagrazia Ruvoletto (Author), Alessandra Biasiolo (Author), Francesco Filippini (Author), Luca Spiezia (Author), Laura Cendron (Author), Patrizia Pontisso (Author)
• Format: Book
• Published: MDPI AG, 2023-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

In the last decades, studies on the inflammatory signaling pathways in multiple pathological contexts have revealed new targets for novel therapies. Among the family of G-protein-coupled Proteases Activated Receptors, PAR2 was identified as a driver of the inflammatory cascade in many pathologies, r...