A case of malignant transformation of a serous borderline ovarian tumor effectively treated with BRAF/MEK inhibitor combination

• Main Authors: Manrose Singh (Author), Samantha Cornwell (Author), Ariel Shaddaie (Author), Leah Wachsmuth (Author), Ashwin Ragupathi (Author), Leonidas Salichos (Author), Sandra Nissel-Horowitz (Author), Rajasree Roy (Author), Maria Plummer (Author), Dong Zhang (Author), Bhoomi Mehrotra (Author)
• Format: Book
• Published: Elsevier, 2024-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

We describe a patient diagnosed with a metastatic adenocarcinoma of Müllerian origin, harboring a BRAF V600E mutation, ten years after being treated for a serous borderline tumor (SBOT). While BRAF mutations in the setting of SBOTs are common, they have been typically associated with a low chance o...