Mathematical Model to Predict Skin Concentration after Topical Application of Drugs

• Ngā kaituhi matua: Hiroaki Todo (Author), Takeshi Oshizaka (Author), Wesam R. Kadhum (Author), Kenji Sugibayashi (Author)
• Hōputu: Pukapuka
• I whakaputaina: MDPI AG, 2013-12-01T00:00:00Z.
• Ngā marau: article
• Urunga tuihono: Connect to this object online.

Skin permeation experiments have been broadly done since 1970s to 1980s as an evaluation method for transdermal drug delivery systems. In topically applied drug and cosmetic formulations, skin concentration of chemical compounds is more important than their skin permeations, because primary target s...