Differential Internalization of Thrombin-Derived Host Defense Peptides into Monocytes and Macrophages

• Główni autorzy: Finja C. Hansen (Autor), Aftab Nadeem (Autor), Kathryn L. Browning (Autor), Mario Campana (Autor), Artur Schmidtchen (Autor), Mariena J.A. van der Plas (Autor)
• Format: Książka
• Wydane: Karger Publishers, 2021-12-01T00:00:00Z.
• Hasła przedmiotowe: article
• Dostęp online: Connect to this object online.

Proteolytic cleavage of thrombin generates C-terminal host defense peptides exerting multiple immunomodulatory effects in response to bacterial stimuli. Previously, we reported that thrombin-derived C-terminal peptides (TCPs) are internalized in monocytes and macrophages in a time- and temperature-d...