Metformin Attenuates Bone Cancer Pain by Reducing TRPV1 and ASIC3 Expression

• Main Authors: He-Ya Qian (Author), Fang Zhou (Author), Rui Wu (Author), Xiao-Jun Cao (Author), Tao Zhu (Author), Hao-Dong Yuan (Author), Ya-Nan Chen (Author), Ping-An Zhang (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Bone cancer pain (BCP) is a common pathologic pain associated with destruction of bone and pathological reconstruction of nervous system. Current treatment strategies in clinical is inadequate and have unacceptable side effects due to the unclear pathology mechanism. In the present study, we showed...