4-HIL mitigates type-2 diabetic complications through inhibiting inflammation and Nrf2 mediated oxidative stress in rats

• Main Authors: Rupali Singh (Author), Karan Singh Yadav (Author), Ramanand Prajapati (Author), Sharad Sharma (Author), Srikanta Kumar Rath (Author), Tadigoppula Narender (Author), Madhav Nilakanth Mugale (Author)
• Format: Book
• Published: Elsevier, 2022-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Hyperglycemia induced diabetic complications as well as dysfunction of multiple organs is closely related to the increased inflammation and oxidative stress (OS). 4-hydroxyisoleucine (4-HIL), a major constituent of Trigonella foenum-graecum L. shown to have anti-diabetic effects. However...