Zebrafish modeling of intestinal injury, bacterial exposures and medications defines epithelial in vivo responses relevant to human inflammatory bowel disease

• Prif Awduron: Ling-shiang Chuang (Awdur), Joshua Morrison (Awdur), Nai-yun Hsu (Awdur), Philippe Ronel Labrias (Awdur), Shikha Nayar (Awdur), Ernie Chen (Awdur), Nicole Villaverde (Awdur), Jody Ann Facey (Awdur), Gilles Boschetti (Awdur), Mamta Giri (Awdur), Mireia Castillo-Martin (Awdur), Tin Htwe Thin (Awdur), Yashoda Sharma (Awdur), Jaime Chu (Awdur), Judy H. Cho (Awdur)
• Fformat: Llyfr
• Cyhoeddwyd: The Company of Biologists, 2019-08-01T00:00:00Z.
• Pynciau: article
• Mynediad Ar-lein: Connect to this object online.

Genome-wide association studies have identified over 200 genomic loci associated with inflammatory bowel disease (IBD). High-effect risk alleles define key roles for genes involved in bacterial response and innate defense. More high-throughput in vivo systems are required to rapidly evaluate therape...