MnTE-2-PyP Suppresses Prostate Cancer Cell Growth via H₂O₂ Production

• Egile Nagusiak: Yuxiang Zhu (Egilea), Elizabeth A. Kosmacek (Egilea), Arpita Chatterjee (Egilea), Rebecca E. Oberley-Deegan (Egilea)
• Formatua: Liburua
• Argitaratua: MDPI AG, 2020-06-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

Prostate cancer patients are often treated with radiotherapy. MnTE-2-PyP, a superoxide dismutase (SOD) mimic, is a known radioprotector of normal tissues. Our recent work demonstrated that MnTE-2-PyP also inhibits prostate cancer progression with radiotherapy; however, the mechanisms remain unclear....