Combination of Betulinic Acid Fragments and Carbonic Anhydrase Inhibitors-A New Drug Targeting Approach

Human carbonic anhydrase IX (hCA IX) is a zinc(II)-dependent metalloenzyme that plays a critical role in the conversion of carbon dioxide and water to protons and bicarbonate. It is a membrane-bound protein with an extracellular catalytic center that is predominantly overexpressed in solid hypoxic t...

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Main Authors: Matthias Bache (Author), Niels V. Heise (Author), Andreas Thiel (Author), Anne Funtan (Author), Franziska Seifert (Author), Marina Petrenko (Author), Antje Güttler (Author), Sarah Brandt (Author), Thomas Mueller (Author), Dirk Vordermark (Author), Iris Thondorf (Author), René Csuk (Author), Reinhard Paschke (Author)
Format: Book
Published: MDPI AG, 2024-03-01T00:00:00Z.
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