Total Glucosides of Paeony Alleviate Cell Apoptosis and Inflammation by Targeting the Long Noncoding RNA XIST/MicroRNA-124-3p/ITGB1 Axis in Renal Ischemia/Reperfusion Injury

• Главные авторы: Fang Chen (Автор), Yi Hu (Автор), Yuetao Xie (Автор), Zonghui Zhao (Автор), Lin Ma (Автор), Zhili Li (Автор), Wanlong Tan (Автор)
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• Опубликовано: Hindawi Limited, 2020-01-01T00:00:00Z.
• Предметы: article
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Objective. Renal ischemia/reperfusion injury (RI/RI) is the main cause of acute kidney injury. Total glucosides of paeony (TGP) are a traditional Chinese medicine. This study was aimed at exploring the role of TGP in RI/RI and its underlying mechanism of action. Methods. Rat RI/RI models were constr...