Pioglitazone Improves Mitochondrial Function in the Remnant Kidney and Protects against Renal Fibrosis in 5/6 Nephrectomized Rats

• Main Authors: Li Sun (Author), Quan Yuan (Author), Tianhua Xu (Author), Li Yao (Author), Jiangmin Feng (Author), Jianfei Ma (Author), Lining Wang (Author), Changlong Lu (Author), Danan Wang (Author)
• Format: Book
• Published: Frontiers Media S.A., 2017-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Pioglitazone is a type of peroxisome proliferator-activated receptor γ (PPARγ) agonist and has been demonstrated to be effective in chronic kidney diseases (CKD) treatment. However, the underlying mechanism involved in the renoprotection of pioglitazone has not been fully revealed. In the present st...