Considerations for feature selection using gene pairs and applications in large-scale dataset integration, novel oncogene discovery, and interpretable cancer screening

• Ngā kaituhi matua: Laura Moody (Author), Hong Chen (Author), Yuan-Xiang Pan (Author)
• Hōputu: Pukapuka
• I whakaputaina: BMC, 2020-10-01T00:00:00Z.
• Ngā marau: article
• Urunga tuihono: Connect to this object online.

Abstract Background Advancements in transcriptomic profiling have led to the emergence of new challenges regarding data integration and interpretability. Variability between measurement platforms makes it difficult to compare between cohorts, and large numbers of gene features have encouraged the us...