The benefit of combinations of oximes for the ability of antidotal treatment to counteract sarin-induced brain damage in rats

• Main Authors: Filip Caisberger (Author), Jaroslav Pejchal (Author), Jan Misik (Author), Jiri Kassa (Author), Martin Valis (Author), Kamil Kuca (Author)
• Format: Book
• Published: BMC, 2018-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background The aim of our study was to compare the ability of two combinations of oximes (HI-6 + trimedoxime and HI-6 + K203) with atropine to counteract acute sarin-induced brain damage with the efficacy of antidotal treatment involving single oxime (HI-6) and atropin using in vivo methods...