Targeted Propolis-Loaded Poly (Butyl) Cyanoacrylate Nanoparticles: An Alternative Drug Delivery Tool for the Treatment of Cryptococcal Meningitis

• Main Authors: Patcharin Thammasit (Author), Chayada Sitthidet Tharinjaroen (Author), Yingmanee Tragoolpua (Author), Volker Rickerts (Author), Radostina Georgieva (Author), Hans Bäumler (Author), Khajornsak Tragoolpua (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

In this study, we describe a nano-carrier system for propolis that is able to cross an in vitro model of the blood-brain barrier (BBB) and effectively reduce the virulence of Cryptococcus neoformans in animal models. Antimicrobial properties of propolis have been widely studied. However, propolis ap...