Total Adiponectin Is Inversely Associated with Platelet Activation and CHA2DS2-VASc Score in Anticoagulated Patients with Atrial Fibrillation

• Main Authors: Roberto Carnevale (Author), Daniele Pastori (Author), Mariangela Peruzzi (Author), Elena De Falco (Author), Isotta Chimenti (Author), Giuseppe Biondi-Zoccai (Author), Ernesto Greco (Author), Antonino G. M. Marullo (Author), Cristina Nocella (Author), Francesco Violi (Author), Pasquale Pignatelli (Author), Camilla Calvieri (Author), Giacomo Frati (Author)
• Format: Book
• Published: Hindawi Limited, 2014-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background. Adiponectin (APN) possesses anti-inflammatory and antiatherogenic effects. Atrial fibrillation (AF) is burdened by enhanced systemic inflammation and platelet activation, as documented by increased blood levels of soluble CD40L (sCD40L). The interplay between APN and platelet activation...