The Long-Term DEHP Exposure Confers Multidrug Resistance of Triple-Negative Breast Cancer Cells through ABC Transporters and Intracellular ROS

• Main Authors: Mahendra Jadhao (Author), Eing-Mei Tsai (Author), Ho-Chun Yang (Author), Yih-Fung Chen (Author), Shih-Shin Liang (Author), Tsu-Nai Wang (Author), Yen-Ni Teng (Author), Hurng-Wern Huang (Author), Li-Fang Wang (Author), Chien-Chih Chiu (Author)
• Format: Book
• Published: MDPI AG, 2021-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The characteristics of phthalates had been thought to be similar to endocrine disruptors, which increases cancer risk. The role of phthalates in acquired drug resistance remains unclear. In this study, we investigated the effect of di-(2-ethylhexyl) phthalate (DEHP) on acquired drug resistance in br...