Engineering an anti-CD52 antibody for enhanced deamidation stability

Engineering an anti-CD52 antibody for enhanced deamidation stability

Deamidation evaluation and mitigation is an important aspect of therapeutic antibody developability assessment. We investigated the structure and function of the Asn-Gly deamidation in a human anti-CD52 IgG1 antibody light chain complementarity-determining region 1, and risk mitigation through prote...

Full description

Saved in:
Bibliographic Details
Main Authors: Huawei Qiu (Author), Ronnie Wei (Author), Julie Jaworski (Author), Ekaterina Boudanova (Author), Heather Hughes (Author), Scott VanPatten (Author), Anders Lund (Author), Jaime Day (Author), Yanfeng Zhou (Author), Tracey McSherry (Author), Clark Q. Pan (Author), Rebecca Sendak (Author)
Format: Book
Published: Taylor & Francis Group, 2019-10-01T00:00:00Z.
Subjects:
article
Online Access:Connect to this object online.
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

Connect to this object online.

3rd Floor Main Library

Holdings details from 3rd Floor Main Library
Call Number: A1234.567
Copy 1 Available

Similar Items