Critical Role of HAX-1 in Promoting Avian Influenza Virus Replication in Lung Epithelial Cells

• Váldodahkkit: Xue Li (Dahkki), Bingqian Qu (Dahkki), Ganlin He (Dahkki), Carol J. Cardona (Dahkki), Yongchun Song (Dahkki), Zheng Xing (Dahkki)
• Materiálatiipa: Girji
• Almmustuhtton: Hindawi Limited, 2018-01-01T00:00:00Z.
• Fáttát: article
• Liŋkkat: Connect to this object online.

The PB1-F2 protein of influenza A virus has been considered a virulence factor, but its function in inducing apoptosis may be of disadvantage to viral replication. Host mechanisms to regulate PB1-F2-induced apoptosis remain unknown. We generated a PB1-F2-deficient avian influenza virus (AIV) H9N2 an...