Obesity alters the mouse endometrial transcriptome in a cell context-dependent manner

• Main Authors: Mike R. Wilson (Author), Hilary Skalski (Author), Jake J. Reske (Author), Marc Wegener (Author), Marie Adams (Author), Galen Hostetter (Author), Hanne M. Hoffmann (Author), Jamie J. Bernard (Author), Victoria L. Bae-Jump (Author), Jose M. Teixeira (Author), Ronald L. Chandler (Author)
• Format: Book
• Published: BMC, 2022-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Obesity impacts fertility and is positively correlated with endometrial hyperplasia and endometrial cancer occurrence. Endometrial epithelia often harbor disease driver-mutations, while endometrial stroma are highly regulative of neighboring epithelia. Here, we sought to determine distinct...