Stimulation of wild-type, F508del- and G551D-CFTR chloride channels by non toxic modified pyrrolo[2,3-b]pyrazine derivatives

Stimulation of wild-type, F508del- and G551D-CFTR chloride channels by non toxic modified pyrrolo[2,3-b]pyrazine derivatives

Cystic Fibrosis is a major inherited disorder involving abnormalities of fluid and electrolyte transport in a number of different organs due to abnormal function of Cystic Fibrosis Transmembrane conductance Regulator (CFTR) protein. We recently identified a family of CFTR activators, which contains...

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Main Authors: Luc eDannhoffer (Author), Arnaud eBillet (Author), Mathilde eJollivet (Author), Patricia eMelin-Heschel (Author), Christelle eFaveau (Author), Frederic eBecq (Author)
Format: Book
Published: Frontiers Media S.A., 2011-08-01T00:00:00Z.
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3rd Floor Main Library

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