Pharmacogenomic Predictors of Antibiotic-Associated Drug-Induced Liver Injury in Critically Ill Children: Observational Study Results

• Auteurs principaux: A. V. Vlasova (Auteur), Yu. F. Shubina (Auteur), I. R. Gaziev (Auteur), D. A. Sychev (Auteur)
• Format: Livre
• Publié: Ministry of Health of the Russian Federation, Federal State Budgetary Institution «Scientific Centre for Expert Evaluation of Medicinal Products», 2024-07-01T00:00:00Z.
• Sujets: article
• Accès en ligne: Connect to this object online.

INTRODUCTION. The pathogenesis of antibiotic-associated drug-induced liver injury (DILI) in children has not been fully elucidated to date. Certain genotypes in patients increase the probability of developing DILI. Therefore, the identification of pharmacogenetic markers associated with DILI in chil...