The Delayed Neuroprotective Effect of Methylene Blue in Experimental Rat Brain Trauma

• Main Authors: Elizaveta E. Genrikhs (Author), Elena V. Stelmashook (Author), Dmitriy N. Voronkov (Author), Svetlana V. Novikova (Author), Olga P. Alexandrova (Author), Mikhail V. Gulyaev (Author), Nickolay K. Isaev (Author)
• Format: Book
• Published: MDPI AG, 2020-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

After traumatic brain injury (TBI), an increase in dysfunction of the limbs contralateral to injury focus was observed. Using different behavioral tests, we found that a single intravenous injection of methylene blue (MB, 1 mg/kg) 30 min after the injury reduced the impairment of the motor functions...