Development and Characterization of Cationic Nanostructured Lipid Carriers as Drug Delivery Systems for miRNA-27a

• Những tác giả chính: Amina Tucak-Smajić (Tác giả), Ivana Ruseska (Tác giả), Ilse Letofsky-Papst (Tác giả), Edina Vranić (Tác giả), Andreas Zimmer (Tác giả)
• Định dạng: Sách
• Được phát hành: MDPI AG, 2023-07-01T00:00:00Z.
• Những chủ đề: article
• Truy cập trực tuyến: Connect to this object online.

Although miRNA-27a has been identified as a promising candidate for miRNA mimic therapy of obesity, its application is limited due to enzymatic degradation and low membrane permeation. To overcome these problems, we developed cationic nanostructured lipid carriers (cNLCs) using high-pressure homogen...