Cmarr/miR-540-3p axis promotes cardiomyocyte maturation transition by orchestrating Dtna expression

• Main Authors: Yukang Wu (Author), Xudong Guo (Author), Tong Han (Author), Ke Feng (Author), Peng Zhang (Author), Yanxin Xu (Author), Yiwei Yang (Author), Yuchen Xia (Author), Yang Chen (Author), Jiajie Xi (Author), Huangtian Yang (Author), Xiaoping Wan (Author), Jiuhong Kang (Author)
• Format: Book
• Published: Elsevier, 2022-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The immature phenotype of embryonic stem cell-derived cardiomyocytes (ESC-CMs) limits their application. However, the molecular mechanisms of cardiomyocyte maturation remain largely unexplored. This study found that overexpression of long noncoding RNA (lncRNA)-Cmarr, which was highly expressed in c...