Single-particle cryo-EM of the ryanodine receptor channel

• Váldodahkkit: Mariah R. Baker (Dahkki), Guizhen Fan (Dahkki), Irina I. Serysheva (Dahkki)
• Materiálatiipa: Girji
• Almmustuhtton: PAGEPress Publications, 2015-01-01T00:00:00Z.
• Fáttát: article
• Liŋkkat: Connect to this object online.

Ryanodine receptors (RyRs) are tetrameric ligand-gated Ca2+ release channels that are responsible for the increase of cytosolic Ca2+ concentration leading to muscle contraction. Our current understanding of RyR channel gating and regulation is greatly limited due to the lack of a high-resolution str...