Genetic and Epigenetic Alterations of <i>CDH1</i> Regulatory Regions in Hereditary and Sporadic Gastric Cancer

• Автори: Gianluca Tedaldi (Автор), Chiara Molinari (Автор), Celina São José (Автор), Rita Barbosa-Matos (Автор), Ana André (Автор), Rita Danesi (Автор), Valentina Arcangeli (Автор), Mila Ravegnani (Автор), Luca Saragoni (Автор), Paolo Morgagni (Автор), Francesca Rebuzzi (Автор), Matteo Canale (Автор), Sara Pignatta (Автор), Elisa Ferracci (Автор), Giovanni Martinelli (Автор), Guglielmina Nadia Ranzani (Автор), Carla Oliveira (Автор), Daniele Calistri (Автор), Paola Ulivi (Автор)
• Формат: Книга
• Опубліковано: MDPI AG, 2021-05-01T00:00:00Z.
• Предмети: article
• Онлайн доступ: Connect to this object online.

E-cadherin is a key player in gastric cancer (GC) and germline alterations of <i>CDH1</i>, its encoding gene, are responsible for Hereditary Diffuse Gastric Cancer (HDGC) syndrome. This study aimed at elucidating the role of genetic variants and DNA methylation of <i>CDH1</i>...