Genetic and Epigenetic Alterations of <i>CDH1</i> Regulatory Regions in Hereditary and Sporadic Gastric Cancer

• मुख्य लेखकों: Gianluca Tedaldi (लेखक), Chiara Molinari (लेखक), Celina São José (लेखक), Rita Barbosa-Matos (लेखक), Ana André (लेखक), Rita Danesi (लेखक), Valentina Arcangeli (लेखक), Mila Ravegnani (लेखक), Luca Saragoni (लेखक), Paolo Morgagni (लेखक), Francesca Rebuzzi (लेखक), Matteo Canale (लेखक), Sara Pignatta (लेखक), Elisa Ferracci (लेखक), Giovanni Martinelli (लेखक), Guglielmina Nadia Ranzani (लेखक), Carla Oliveira (लेखक), Daniele Calistri (लेखक), Paola Ulivi (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: MDPI AG, 2021-05-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

E-cadherin is a key player in gastric cancer (GC) and germline alterations of <i>CDH1</i>, its encoding gene, are responsible for Hereditary Diffuse Gastric Cancer (HDGC) syndrome. This study aimed at elucidating the role of genetic variants and DNA methylation of <i>CDH1</i>...