Development of a novel DNA sequencing method not only for hepatitis B virus genotyping but also for drug resistant mutation detection

• Main Authors: Wang Fanjun (Author), Lu Lili (Author), Yu Changshun (Author), Lv Zhanwu (Author), Luo Xuelian (Author), Wan Chao (Author), Hu Zhaohui (Author), Zhu Qinyi (Author), Deng Youping (Author), Zhang Chuyu (Author)
• Format: Book
• Published: BMC, 2013-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>In HBV-infected patients, different genotypes of the hepatitis B virus influence liver disease progression and response to antiviral therapy. Moreover, long-term antiviral therapy will eventually select for drug-resistant mutants. De...