Gestational Exposure to Sodium Valproate Disrupts Fasciculation of the Mesotelencephalic Dopaminergic Tract, With a Selective Reduction of Dopaminergic Output From the Ventral Tegmental Area

• Main Authors: Ágota Ádám (Author), Róbert Kemecsei (Author), Verónica Company (Author), Raquel Murcia-Ramón (Author), Iris Juarez (Author), László I. Gerecsei (Author), Gergely Zachar (Author), Diego Echevarría (Author), Eduardo Puelles (Author), Salvador Martínez (Author), András Csillag (Author)
• Format: Book
• Published: Frontiers Media S.A., 2020-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Gestational exposure to valproic acid (VPA) is known to cause behavioral deficits of sociability, matching similar alterations in human autism spectrum disorder (ASD). Available data are scarce on the neuromorphological changes in VPA-exposed animals. Here, we focused on alterations of the dopaminer...