Repeated Treatment With the Traditional Medicine Unsei-in Inhibits Substance P-Induced Itch-Associated Responses Through Downregulation of the Expression of Nitric Oxide Synthase 1 in Mice

• Autores principales: Tsugunobu Andoh (Autor), Ali Al-Akeel (Autor), Kenichiro Tsujii (Autor), Hiroshi Nojima (Autor), Yasushi Kuraishi (Autor)
• Formato: Libro
• Publicado: Elsevier, 2004-01-01T00:00:00Z.
• Materias: article
• Acceso en línea: Connect to this object online.

Unsei-in inhibits substance P (SP)-induced scratching of mice after repeated administration. The involvement of cutaneous nitric oxide (NO) in the SP-induced scratching led us to investigate the effects of Unsei-in on the cutaneous NO system in mice. Seven-day oral administration of Unsei-in (300, b...