Repeated Treatment With the Traditional Medicine Unsei-in Inhibits Substance P-Induced Itch-Associated Responses Through Downregulation of the Expression of Nitric Oxide Synthase 1 in Mice

• Auteurs principaux: Tsugunobu Andoh (Auteur), Ali Al-Akeel (Auteur), Kenichiro Tsujii (Auteur), Hiroshi Nojima (Auteur), Yasushi Kuraishi (Auteur)
• Format: Livre
• Publié: Elsevier, 2004-01-01T00:00:00Z.
• Sujets: article
• Accès en ligne: Connect to this object online.

Unsei-in inhibits substance P (SP)-induced scratching of mice after repeated administration. The involvement of cutaneous nitric oxide (NO) in the SP-induced scratching led us to investigate the effects of Unsei-in on the cutaneous NO system in mice. Seven-day oral administration of Unsei-in (300, b...