Monitoring of immune activation using biochemical changes in a porcine model of cardiac arrest

• Main Authors: Anton Amann (Author), Bernhard Widner (Author), Josef Rieder (Author), Herwig Antretter (Author), Georg Hoffmann (Author), Viktoria Mayr (Author), Hans-Ulrich Strohmenger (Author), Dietmar Fuchs (Author)
• Format: Book
• Published: Hindawi Limited, 2001-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

In animal models, immune activation is often difficult to assess because of the limited availability of specific assays to detect cytokine activities. In human monocytes/macrophages, interferon-γ induces increased production of neopterin and an enhanced activity of indoleamine 2,3-dioxygenase, which...