Eupatilin attenuates the senescence of nucleus pulposus cells and mitigates intervertebral disc degeneration via inhibition of the MAPK/NF-κB signaling pathway

• Main Authors: Huan Yang (Author), Xiao Yang (Author), Kewei Rong (Author), Jiarong Liang (Author), Zhengting Wang (Author), Jie Zhao (Author), Pu Zhang (Author), Yijie Li (Author), Lihuan Wang (Author), Hui Ma (Author), Bin Ye (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Intervertebral disc degeneration (IDD) is the main cause of low back pain. An increasing number of studies have suggested that inflammatory response or the senescence of nucleus pulposus (NP) cells is strongly associated with the progress of IDD. Eupatilin, the main flavonoid extracted from Artemisi...