Potential selection of antimony and methotrexate cross-resistance in Leishmania infantum circulating strains.

• Main Authors: Lorena Bernardo (Author), Ana Victoria Ibarra-Meneses (Author), Noelie Douanne (Author), Audrey Corbeil (Author), Jose Carlos Solana (Author), Francis Beaudry (Author), Eugenia Carrillo (Author), Javier Moreno (Author), Christopher Fernandez-Prada (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2024-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<h4>Background</h4>Visceral leishmaniasis (VL) resolution depends on a wide range of factors, including the instauration of an effective treatment coupled to a functional host immune system. Patients with a depressed immune system, like the ones receiving methotrexate (MTX), are at highe...