Clinicopathologic diagnosis of dVIN related vulvar squamous cell carcinoma: An extended appraisal from a tertiary women's hospital

• Main Authors: Tiannan Wang (Author), Vandana Baloda (Author), Lakshmi Harinath (Author), Terrell Jones (Author), Huina Zhang (Author), Rohit Bhargava (Author), Chengquan Zhao (Author)
• Format: Book
• Published: BMJ Publishing Group, 2023-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Differentiated vulvar intraepithelial neoplasia (dVIN) is a non-human papilloma virus (HPV)-related high-grade precursor lesion to vulvar squamous cell carcinoma (vSCCa). Although TP53 gene mutations have been identified in 80% of dVIN, its role in dVIN pathogenesis as well as malignant...