Clinicopathologic diagnosis of dVIN related vulvar squamous cell carcinoma: An extended appraisal from a tertiary women's hospital

• Главные авторы: Tiannan Wang (Автор), Vandana Baloda (Автор), Lakshmi Harinath (Автор), Terrell Jones (Автор), Huina Zhang (Автор), Rohit Bhargava (Автор), Chengquan Zhao (Автор)
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• Опубликовано: BMJ Publishing Group, 2023-03-01T00:00:00Z.
• Предметы: article
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Background: Differentiated vulvar intraepithelial neoplasia (dVIN) is a non-human papilloma virus (HPV)-related high-grade precursor lesion to vulvar squamous cell carcinoma (vSCCa). Although TP53 gene mutations have been identified in 80% of dVIN, its role in dVIN pathogenesis as well as malignant...