Association of miR-181c/d gene locus rs8108402 C/T polymorphism with susceptibility to Kawasaki disease in Chinese children

• Main Authors: Meiqing Yao (Author), Qin He (Author), Manqiong Yang (Author), Zhixiang Wu (Author), Ying Li (Author), Min Kong (Author), Zhijuan Kang (Author), Lu Yi (Author), Yanan Hu (Author), Lihua Huang (Author), Zhuoying Li (Author), Zuocheng Yang (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

BackgroundKawasaki disease (KD) is an acute systemic vasculitis of unknown etiology. The rs8108402 C/T single nucleotide polymorphism (SNP) is located in the promoter region of miR-181-c/d gene and the intron of Nanos3 gene. The miR-181 family contributes to the pathogenesis of cardiovascular and in...