Sinensetin Reduces Osteoarthritis Pathology in the Tert-Butyl Hydroperoxide-Treated Chondrocytes and the Destabilization of the Medial Meniscus Model Mice via the AMPK/mTOR Signaling Pathway

As a common degenerative disease, osteoarthritis (OA) usually causes disability in the elderly and socioeconomic burden. Previous studies have shown that proper autophagy has a protective effect on OA. Sinensetin (Sin) is a methylated flavonoid derived from citrus fruits. Studies have shown that Sin...

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Hlavní autoři: Wenxian Zhou (Autor), Yifeng Shi (Autor), Hui Wang (Autor), Caiyu Yu (Autor), Huanqing Zhu (Autor), Aimin Wu (Autor)
Médium: Kniha
Vydáno: Frontiers Media S.A., 2021-07-01T00:00:00Z.
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