"cART intensification by the HIV-1 Tat B clade vaccine: progress to phase III efficacy studies"

• Main Authors: Aurelio Cafaro (Author), Cecilia Sgadari (Author), Orietta Picconi (Author), Antonella Tripiciano (Author), Sonia Moretti (Author), Vittorio Francavilla (Author), Maria Rosaria Pavone Cossut (Author), Stefano Buttò (Author), Giovanni Cozzone (Author), Fabrizio Ensoli (Author), Paolo Monini (Author), Barbara Ensoli (Author)
• Format: Book
• Published: Taylor & Francis Group, 2018-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Introduction: In spite of its success at suppressing HIV replication, combination antiretroviral therapy (cART) only partially reduces immune dysregulation and loss of immune functions. These cART-unmet needs appear to be due to persistent virus replication and cell-to-cell transmission in reservoir...