NOX5 is expressed aberrantly but not a critical pathogenetic gene in Hirschsprung disease

• Main Authors: Jing Wang (Author), Jun Xiao (Author), Xinyao Meng (Author), Xufeng Chu (Author), Di Di Zhuansun (Author), Bo Xiong (Author), Jiexiong Feng (Author)
• Format: Book
• Published: BMC, 2021-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Hirschsprung disease (HSCR) is a congenital disorder characterized by the absence of intramural ganglion cells in the distal gastrointestinal tract (GI), which results in tonic contraction of the aganglionic gut segment and functional intestinal obstruction. Recent studies have s...