Stoichiometry of multi-specific immune checkpoint RNA Abs for T cell activation and tumor inhibition using ultra-stable RNA nanoparticles

Immunotherapy has become a revolutionary subject in cancer therapy during the past few years. Immune checkpoint-targeting antibodies (Abs) could boost anticancer immune responses. However, certain protein-based immunotherapies revealed side effects and unfavorable biodistribution, so effective non-p...

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Autores principales: Dan Shu (Autor), Long Zhang (Autor), Xuefeng Bai (Autor), Jianhua Yu (Autor), Peixuan Guo (Autor)
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Publicado: Elsevier, 2021-06-01T00:00:00Z.
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