Stoichiometry of multi-specific immune checkpoint RNA Abs for T cell activation and tumor inhibition using ultra-stable RNA nanoparticles

• Asıl Yazarlar: Dan Shu (Yazar), Long Zhang (Yazar), Xuefeng Bai (Yazar), Jianhua Yu (Yazar), Peixuan Guo (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: Elsevier, 2021-06-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

Immunotherapy has become a revolutionary subject in cancer therapy during the past few years. Immune checkpoint-targeting antibodies (Abs) could boost anticancer immune responses. However, certain protein-based immunotherapies revealed side effects and unfavorable biodistribution, so effective non-p...