Propofol Protects Myocardium From Ischemia/Reperfusion Injury by Inhibiting Ferroptosis Through the AKT/p53 Signaling Pathway

• Main Authors: Shengqiang Li (Author), Zhen Lei (Author), Xiaomei Yang (Author), Meng Zhao (Author), Yonghao Hou (Author), Di Wang (Author), Shuhai Tang (Author), Jingxin Li (Author), Jingui Yu (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The molecular mechanism underlying the protective role of propofol against myocardial ischemia/reperfusion (I/R) injury remains poorly understood. Previous studies have shown that ferroptosis is an imperative pathological process in myocardial I/R injury. We hypothesized that propofol prevents myoca...