MLN2238 exerts its anti-tumor effects via regulating ROS/JNK/mitochondrial signaling pathways in intrahepatic cholangiocarcinoma

• Main Authors: Hao Xu (Author), Guangyu Xu (Author), Qianhui Xu (Author), Chang Xu (Author), Xiaohu Zhou (Author), Yang Bai (Author), Lu Yin (Author), Yuan Ding (Author), Weilin Wang (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Intrahepatic Cholangiocarcinoma (iCCA) is a highly malignant tumor with limited treatment options that contributes largely to cancer-related deaths worldwide. Compared with traditional transcriptomic analysis, single-cell RNA sequencing (scRNA-seq) is emerging as a more advanced and popu...